A national study of the clinical management of HIV-positive women in Australia: what are the successes and where are the gaps?

Giles, Michelle L., MacPhail, Aleece, Bell, Charlotte, Bradshaw, Catriona S., Furner, Virginia, Gunathilake, Manoji, John, Mina, Krishnaswamy, Sushena, Martin, Sarah J., Ooi, Catriona, Owen, Louise, Russell, Darren, Street, Alan, and Post, Jeffrey J. (2019) A national study of the clinical management of HIV-positive women in Australia: what are the successes and where are the gaps? Sexual Health, 16 (3). pp. 282-288.

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Abstract

Background Women comprise similar to 10% of people living with HIV in Australia, so are often underrepresented in research. Methods: This study invited clinicians providing care to women living with HIV to complete an anonymous survey containing questions related to four key areas: HIV (including diagnosis, treatment and virological outcomes), reproductive health (including sexual activity, contraception, pregnancy and outcomes) and linkage and retention in care. Results: In total, 484 surveys were received, with responses from all states and territories. Most women living with HIV in Australia are on treatment (>90%) and virologically suppressed (>90% have a viral load <50 copies mL(-1)). Almost 75% of women have had at least one switch in treatment (with toxicity almost as common as simplification as the indication). Treatment interruption is also relatively common, but is more likely the longer a woman has been diagnosed, if she is on benefits (P = 0.007) and is the primary carer of children without a partner (P = 0.001). In Australia, women living with HIV are a diverse heterogeneous group, with over 70 different countries of birth and almost half speaking a language other than English at home. Mental health diagnosis was the most common co-morbid condition identified. A total of 21% of women were post-menopausal, with 42% reporting symptoms to their healthcare provider, but only 17% were receiving treatment for symptoms attributed to menopause. Conclusions: As well as strategies to support women vulnerable to treatment interruption, important areas for future investment in research and clinical care include co-morbid mental health and menopause symptoms and treatment.

Item ID: 60087
Item Type: Article (Research - C1)
ISSN: 1449-8987
Keywords: antiretroviral treatment, interruption, menopause, reproductive health, switching
Copyright Information: (C) CSIRO 2019
Funders: Gilead Sciences
Date Deposited: 31 Jul 2019 07:48
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111799 Public Health and Health Services not elsewhere classified @ 30%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111706 Epidemiology @ 70%
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