Factors influencing breast cancer outcomes in Australia: a systematic review

Ho-Huyn, Albert, Tran, Alex, Bray, Gerard, Abbot, Samuel, Elston, Tim, Gunnarsson, Ronny, and de Costa, Alan (2019) Factors influencing breast cancer outcomes in Australia: a systematic review. European Journal of Cancer Care, 28. e13038.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: https://doi.org/10.1111/ecc.13038
 
1
3


Abstract

Purpose: This systematic review evaluates factors influencing breast cancer outcomes for women treated in Australia, facilitating the exploration of disparities in breast cancer outcomes for certain groups of women in Australia.

Method: A systematic literature search was performed using MEDLINE and Scopus focusing on breast cancer in Australia with outcome measures being breast cancer survival and recurrence with no restrictions on date. Risk of bias was assessed using Cairns Assessment Scale for Observational studies of Risk factors (CASOR).

Results: Fifteen quantitative studies were included: two were high quality, 11 were intermediate quality, and two were low quality. Traditional risk factors such as invasive tumour type, larger size, higher grade and stage, lymph node involvement and absence of hormone receptors were found to be associated with breast cancer mortality. Being younger (<40 years old) and older (>70 years old), having more comorbidities, being of lower socioeconomic status, identifying as Aboriginal or Torres Strait Islander, living in more rural areas or having a mastectomy were factors found to be associated with poorer breast cancer outcomes.

Conclusion: Despite the heterogeneity of the studies, this review identified significant risk factors for breast cancer mortality and recurrence. The use of this data would be most useful in developing evidence‐based interventions and in optimising patient care through creation of a prediction model.

Item ID: 57806
Item Type: Article (Research - C1)
ISSN: 1365-2354
Date Deposited: 18 Sep 2019 01:31
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110323 Surgery @ 33%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111706 Epidemiology @ 33%
11 MEDICAL AND HEALTH SCIENCES > 1112 Oncology and Carcinogenesis > 111202 Cancer Diagnosis @ 34%
SEO Codes: 92 HEALTH > 9202 Health and Support Services > 920204 Evaluation of Health Outcomes @ 50%
92 HEALTH > 9202 Health and Support Services > 920208 Health Inequalities @ 50%
Downloads: Total: 3
Last 12 Months: 1
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page