The effects of expressing antenatal colostrum in women with diabetes in pregnancy: a retrospective cohort study

Casey, Jordan R.R., Banks, Jennifer, Braniff, Kathleen, Buettner, Petra, and Heal, Clare (2019) The effects of expressing antenatal colostrum in women with diabetes in pregnancy: a retrospective cohort study. Australian and New Zealand Journal of Obstetrics and Gynaecology. (In Press)

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Abstract

Background: Some women with diabetes in pregnancy express and store colos-trum in the antenatal period for the purposes of preventing and treating neonatal hypoglycaemia.

Aims: Our primary aim was to compare rates of neonatal hypoglycaemia in babies born to mothers who express and store antenatal colostrum to babies born to mothers who do not.

Materials and methods: Retrospective cohort study involving 357 women with diabetes in pregnancy, who had live, singleton births delivered after 36weeks ges-tation, in a regional hospital in North Queensland (2014–2015). Multivariable bi-nary logistic regression modelling identified independent characteristics associated with primary outcomes.

Results: Eighty women (23%) expressed antenatal colostrum and 223 (62%) did not. One hundred and thirty-one babies (37%) were diagnosed with hypoglycae-mia. Aboriginal and Torres Strait Islander women were less likely to express than Caucasian women (odds ratio (OR) 0.10, 95% confidence interval (CI) 0.01–0.77). There were no significant differences in the rates of hypoglycaemia, or median blood glucose levels in babies born to mothers who expressed antenatal colos-trum compared to babies born to mothers who did not express. Babies born to mothers who expressed were significantly less likely to receive formula in hospital compared to babies born to mothers who did not (OR 0.12, 95% CI 0.05–0.32).

Conclusions: We found no independent association of expressing antenatal colostrum on rates of neonatal hypoglycaemia or median blood glucose levels. Expressing antenatal colostrum may have some benefits to the newborn such as reduced formula consumption in hospital. Further research into other methods of reducing neonatal hypoglycaemia appears warranted.

Item ID: 57625
Item Type: Article (Research - C1)
ISSN: 1479-828X
Keywords: colostrum, diabetes, hypoglycaemia, pregnancy in diabetics, prenatal care
Funders: James Cook University (JCU)
Projects and Grants: JCU-QLD-578961
Date Deposited: 27 Mar 2019 23:44
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111716 Preventive Medicine @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111499 Paediatrics and Reproductive Medicine not elsewhere classified @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920104 Diabetes @ 40%
92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920412 Preventive Medicine @ 60%
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