The open field test for measuring locomotor activity and anxiety-like behavior

Kraeuter, Ann-Katrin, Guest, Paul C., and Sarnyai, Zoltan (2019) The open field test for measuring locomotor activity and anxiety-like behavior. In: Guest, Paul C., (ed.) Pre-Clinical Models: techniques and protocols. Methods in Molecular Biology, 1916 . Springer, New York, NY, USA, pp. 99-103.

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Abstract

The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 x 42 x 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.

Item ID: 57129
Item Type: Book Chapter (Scholarly Work)
ISBN: 978-1-4939-8993-5
Keywords: Open-filed, Locomotion, Psychiatric disorder, Anxiety, Behavior
Date Deposited: 26 Feb 2020 04:00
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1109 Neurosciences > 110903 Central Nervous System @ 60%
17 PSYCHOLOGY AND COGNITIVE SCIENCES > 1701 Psychology > 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) @ 40%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920111 Nervous System and Disorders @ 100%
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