Object burying test for assessment of obsessive compulsive behaviors in mice

Kraeuter, Ann-Katrin, Guest, Paul C., and Sarnyai, Zoltan (2019) Object burying test for assessment of obsessive compulsive behaviors in mice. In: Guest, Paul C., (ed.) Pre-Clinical Models: techniques and protocols. Methods in Molecular Biology, 1916 . Springer, New York, NY, USA, pp. 81-85.

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Obsessive-compulsive disorder (OCD) can occur in several psychiatric illnesses such as autism spectrum disorders (ASD) and it is more prevalent in children. This condition is characterized by repeated and apparently meaningless behaviors such as frequent hand washing, counting, tapping, and rocking. This can disrupt normal socialization and in some cases lead to self-harm. Therefore there is interest in developing more effective therapies for individuals suffering from these conditions. This chapter describes how to conduct the mouse marble burying test as a sensitive measure of compulsive behaviors.

Item ID: 57127
Item Type: Book Chapter (Scholarly Work)
ISBN: 978-1-4939-8993-5
Keywords: Behavior, Obsessive-compulsive disorder, Autism spectrum disorder, Mouse, Marbleburying
Copyright Information: © Springer Science+Business Media, LLC, part of Springer Nature 2019
Date Deposited: 26 Feb 2020 03:57
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1109 Neurosciences > 110903 Central Nervous System @ 60%
17 PSYCHOLOGY AND COGNITIVE SCIENCES > 1701 Psychology > 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) @ 40%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920111 Nervous System and Disorders @ 100%
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