"From Top to Bottom" – Queensland Pre-Exposure Prophylaxis (QPrEPd) demonstration trial and sexually transmitted infections

Yeganeh, S., Cashman, C., Downing, S., Doyle-Adams, S., Elliot, M., Fischer, J., Lukies, S., Pratt, R., Rodriguez, M., Sutcliffe, E., and Russell, D. (2017) "From Top to Bottom" – Queensland Pre-Exposure Prophylaxis (QPrEPd) demonstration trial and sexually transmitted infections. In: [Presented at the Australasian HIV/AIDS Conference 2017]. From: Australasian HIV/AIDS Conference 2017, 6-8 November 2017, Canberra, ACT, Australia.

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Background: In the eighth month since the QPrEPd project rolled out across Queensland, 22 clinical sites have recruited 1695 participants. This paper describes the prevalence of sexually transmitted infections (STIs) in QPrEPd participants at three monthly time points.

Methods: At each time point participants undergo blood testing for HIV and syphilis, urine PCR and pharyngeal swabs and where indicated, anal swabs, for chlamydia and gonorrhoea.

Results: Five participants tested positive for HIV at the screening visit and were all tested at south east Queensland sites. Of the 1,394 participants who completed the entry survey, a third identified that they had not had an HIV screening test within the past 3 months. Of greater concern is the 2.4% who had not been screened within the past 2 years and the 1% who had never been screened in this high risk for HIV population. At screening 12.8% of participants had one or more STIs with little difference at three months (11.3%), however almost half of the three month results are yet to be reported. Interestingly at six months the anal chlamydia prevalence at 9.1% is almost double the 4.5% at screening but this trend may reflect a higher risk of early enrolees and could change once all results have been received. 15% of STI tests conducted at the 11 sites outside of the Queensland south east corner were positive compared to 8.6% in the 11 south east sites.

Conclusion: The preliminary results reveal that a substantial proportion of the population at high risk of HIV acquisition are not following the Australian recommendation of 3 monthly screening. Over time we will explore the regional differences in HIV and STI prevalence and the seeming increasing trend in anal chlamydia.

Item ID: 56978
Item Type: Conference Item (Poster)
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Date Deposited: 04 Dec 2019 00:04
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111799 Public Health and Health Services not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920499 Public Health (excl. Specific Population Health) not elsewhere classified @ 100%
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