Effects of exercise intensity and cardiorespiratory fitness on the acute response of arterial stiffness to exercise in older adults

Perissiou, Maria, Bailey, Tom G., Windsor, Mark, Nam, Michael Chi Yuan, Greaves, Kim, Leicht, Anthony S., Golledge, Jonathan, and Askew, Christopher D. (2018) Effects of exercise intensity and cardiorespiratory fitness on the acute response of arterial stiffness to exercise in older adults. European Journal of Applied Physiology, 118 (8). pp. 1673-1688.

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Abstract

Purpose: Increased arterial stiffness is observed with ageing and in individuals with low cardiorespiratory fitness (O-2peak), and associated with cardiovascular risk. Following an exercise bout, transient arterial stiffness reductions offer short-term benefit, but may depend on exercise intensity. This study assessed the effects of exercise intensity on post-exercise arterial stiffness in older adults with varying fitness levels.

Methods: Fifty-one older adults (72 +/- 5 years) were stratified into fitness tertiles (O-2peak: low-, 22.3 +/- 3.1; mid-, 27.5 +/- 2.4 and high-fit 36.3 +/- 6.5 mL kg(-1) min(-1)). In a randomised order, participants underwent control (no-exercise), moderate-intensity continuous exercise (40% of peak power output; PPO), and higher-intensity interval exercise (70% of PPO) protocols. Pulse wave velocity (PWV), augmentation index (AIx75) and reflection magnitude (RM) were assessed at rest and during 90 min of recovery following each protocol.

Results: After control, delta PWV increased over time (P < 0.001) and delta RM was unchanged. After higher-intensity interval exercise, delta PWV (P < 0.001) and delta RM (P < 0.001) were lower to control in all fitness groups. After moderate-intensity continuous exercise, delta PWV was not different from control in low-fit adults (P = 0.057), but was lower in the mid- and higher-fit older adults. Post-exercise AIx75 was higher to control in all fitness groups (P = 0.001).

Conclusions: In older adults, PWV increases during seated rest and this response is attenuated after higher-intensity interval exercise, regardless of fitness level. This attenuation was also observed after moderate-intensity continuous exercise in adults with higher, but not lower fitness levels. Submaximal exercise reveals differences in the arterial stiffness responses between older adults with higher and lower cardiorespiratory fitness.

Item ID: 54867
Item Type: Article (Research - C1)
ISSN: 1439-6327
Keywords: pulse wave velocity, wave reflection characteristics, exercise intensity, ageing
Funders: National Health and Medical Research Council of Australia (NHMRC), Townsville Hospital
Projects and Grants: NHMRC grant 1000967, NHMRC grant 1022752, NHMRC grant 1079369, NHMRC fellowship 1117061
Date Deposited: 01 Aug 2018 07:34
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1116 Medical Physiology > 111603 Systems Physiology @ 100%
SEO Codes: 92 HEALTH > 9205 Specific Population Health (excl. Indigenous Health) > 920502 Health Related to Ageing @ 100%
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