Tang, Xiaofeng, Liu, Yang, Hou, Haoqing, and You, Tianyan (2010) Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode. Talanta, 80 (5). pp. 2182-2186.

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Abstract

A novel and simple method for the direct and quantitative determination of L-tryptophan (Trp), L-tyrosine (Tyr) and L-cysteine (Cys) was proposed in this work. Carbon nanofibers (CNFs), made by electrospinning technique, were used to modify carbon paste electrode (CPE) without any treatment to study the electrochemical behaviors of the three amino acids using cyclic voltammetry (CV) and constant potential amperometric method. The results demonstrated that the CNFs modified carbon paste electrode (CNF-CPE) exhibited high electrocatalytic activity and good analytical performance towards the oxidation of the three amino acids. The linear ranges of Trp, Tyr and Cys were 0.1–119, 0.2–107 and 0.15–64 μM with correlation coefficients of 0.9994, 0.9985 and 0.9996, respectively. All the detection limits of the analytes were 0.1 μM (S/N = 3). In addition, the CNF-CPE displayed good reproducibility, high sensitivity and good selectivity towards the determination of the amino acids, making it suitable for the determination of Trp, Tyr and Cys in clinical and medicine.

Item ID:	54513
Item Type:	Article (Research - C1)
ISSN:	1873-3573
Keywords:	carbon nanofibers, modified electrode, tryptophan, tyrosine, cysteine, electrocatalytic oxidation
Funders:	National Natural Science Foundation of China (NNSFC), Chinese Academy of Sciences (CAS)
Projects and Grants:	NNSFC 20605020, NNSFC 20875085, CAS KJCX2-YW-H11
Date Deposited:	31 Oct 2018 00:53
FoR Codes:	03 CHEMICAL SCIENCES > 0301 Analytical Chemistry > 030102 Electroanalytical Chemistry @ 100%
SEO Codes:	97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
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