Plant secondary metabolite-derived polymers: a potential approach to develop antimicrobial films

Al-Jumaili, Ahmed, Kumar, Avishek, Bazaka, Kateryna, and Jacob, Mohan V. (2018) Plant secondary metabolite-derived polymers: a potential approach to develop antimicrobial films. Polymers, 10 (5). 515.

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Abstract

The persistent issue of bacterial and fungal colonization of artificial implantable materials and the decreasing efficacy of conventional systemic antibiotics used to treat implant-associated infections has led to the development of a wide range of antifouling and antibacterial strategies. This article reviews one such strategy where inherently biologically active renewable resources, i.e., plant secondary metabolites (PSMs) and their naturally occurring combinations (i.e., essential oils) are used for surface functionalization and synthesis of polymer thin films. With a distinct mode of antibacterial activity, broad spectrum of action, and diversity of available chemistries, plant secondary metabolites present an attractive alternative to conventional antibiotics. However, their conversion from liquid to solid phase without a significant loss of activity is not trivial. Using selected examples, this article shows how plasma techniques provide a sufficiently flexible and chemically reactive environment to enable the synthesis of biologically-active polymer coatings from volatile renewable resources.

Item ID: 54416
Item Type: Article (Research - C1)
ISSN: 2073-4360
Keywords: volatile renewable resources, microbial infection, plant secondary metabolites, antimicrobial essential oils, biologically-active polymers, plasma-assisted technique
Copyright Information: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Date Deposited: 04 Jul 2018 07:35
FoR Codes: 09 ENGINEERING > 0912 Materials Engineering > 091209 Polymers and Plastics @ 100%
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