A randomised controlled trial of consumption of dark chocolate in pregnancy to reduce pre-eclampsia: difficulties in recruitment, allocation and adherence
Gnanendran, Subashini, Porrett, Jemma, Woods, Cindy, Buttrose, Maryke, Jukka, Clare, Hollins, Jane, Robson, Stephen, and de Costa, Caroline (2018) A randomised controlled trial of consumption of dark chocolate in pregnancy to reduce pre-eclampsia: difficulties in recruitment, allocation and adherence. Australian and New Zealand Journal of Obstetrics and Gynaecology, 58 (3). pp. 358-361.
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Abstract
In 2013-2014 we undertook a randomised controlled trial (RCT) to determine whether the daily ingestion of dark chocolate during pregnancy could reduce the incidence of pre-eclampsia in primigravidae. However, after two years we had not succeeded in recruiting more than 3.5% of the number of participants required to answer the research question, and the trial was halted. We also reviewed the literature on this topic and found it to be limited. We report here our findings and discuss the difficulties facing researchers in this area.
| Item ID: | 54344 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 1479-828X |
| Keywords: | dark chocolate, dark chocolate in pregnancy, flavonoid rich dark chocolate, pre-eclampsia |
| Copyright Information: | Copyright © 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists |
| Date Deposited: | 27 Jun 2018 07:34 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3215 Reproductive medicine > 321502 Obstetrics and gynaecology @ 100% |
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