Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing

Liu, Yang, Dong, Yongqiang, Guo, Chun Xian, Cui, Zhiming, Zheng, Lianxi, and Li, Chang Ming (2012) Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing. Electroanalysis, 24 (12). pp. 2348-2353.

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Abstract

A novel nonenzymatic glucose sensor was developed based on well-dispersed gold nanoparticles, which were in situ grown under direction of protein on a reduced graphene oxide modified electrode. This electrode exhibited high electrocatalytic activity towards glucose oxidation without use of any enzyme or mediator. In application for the amperometric detection of glucose, a wide linear range of 0.02-16.6mM, low detection limit of 5μM and good selectivity were obtained. The attractive analytical performances of the proposed glucose sensor, coupled with the facile preparation method, provide a promising electrochemical platform for the development of effective nonenzymatic sensors.

Item ID: 53261
Item Type: Article (Research - C1)
ISSN: 1521-4109
Keywords: glucose, nonenzymatic sensors, gold nanoparticles, reduced graphene oxide, proteins
Funders: Singapore ASTAR, Southwest University, China, Chongqing Key Laboratory for Advanced materials and Technologies of Clean Energies
Projects and Grants: ASTAR 102 170 0142
Date Deposited: 20 Apr 2018 00:45
FoR Codes: 03 CHEMICAL SCIENCES > 0301 Analytical Chemistry > 030102 Electroanalytical Chemistry @ 50%
03 CHEMICAL SCIENCES > 0306 Physical Chemistry (incl Structural) > 030604 Electrochemistry @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
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