Clinical relevance of a p-value: does TXA save lives after trauma or post-partum hemorrhage?

Dobson, Geoffrey P., Doma, Kenji, and Letson, Hayley L. (2017) Clinical relevance of a p-value: does TXA save lives after trauma or post-partum hemorrhage? Journal of Trauma and Acute Care Surgery, 84 (3). pp. 532-536.

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Abstract

[Extract] Tranexamic acid (TXA), an antifibrinolytic agent, has been widely publicized as saving lives after traumatic hemorrhage in the CRASH-2, MATTERs, and PED-TRAX trials and more recently after postpartum hemorrhage (PPH) in the World Maternal Antifibrinolytic (WOMAN) trial. Prophylactic administration of TXA is also increasingly used in major elective and emergency surgery to reduce excessive bleeding, transfusion requirements, and possible reexploration.

Item ID: 52318
Item Type: Article (Research - C1)
ISSN: 2163-0763
Date Deposited: 10 May 2018 22:05
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110305 Emergency Medicine @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920118 Surgical Methods and Procedures @ 100%
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