Metallic biomaterials: current challenges and opportunities

Prasad, Karthika, Bazaka, Olha, Chua, Ming, Rochford, Madison, Fedrick, Liam, Spoor, Jordan, Symes, Richard, Tieppo, Marcus, Collins, Cameron, Cao, Alex, Markwell, David, Ostrikov, Kosya, and Bazaka, Kateryna (2017) Metallic biomaterials: current challenges and opportunities. Materials, 10 (8). 884.

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Abstract

Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.

Item ID: 50863
Item Type: Article (Research - C1)
ISSN: 1996-1944
Keywords: biomaterial, inflammation, implant, advanced materials, surface modification
Additional Information:

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Date Deposited: 27 Sep 2017 07:34
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
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