Bell's palsy in children: current treatment patterns in Australia and New Zealand. A PREDICT study

Babl, Franz E., Gardiner, Kaya K., Kochar, Amit, Wilson, Catherine L., George, Shane A., Zhang, Michael, Furyk, Jeremy, Thosar, Deepali, Cheek, John A., Krieser, David, Rao, Arjun S., Borland, Meredith, Cheng, Nicholas, Phillips, Natalie T., Sinn, Kam K., Neutze, Jocelyn M., Dalziel, Stuart R., and PREDICT (2017) Bell's palsy in children: current treatment patterns in Australia and New Zealand. A PREDICT study. Journal of Paediatrics and Child Health, 53 (4). pp. 339-342.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: https://doi.org/10.1111/jpc.13463
 
9
1


Abstract

Aim: The aetiology and clinical course of Bell's palsy may be different in paediatric and adult patients. There is no randomised placebo controlled trial (RCT) to show effectiveness of prednisolone for Bell's palsy in children. The aim of the study was to assess current practice in paediatric Bell's palsy in Australia and New Zealand Emergency Departments (ED) and determine the feasibility of conducting a multicentre RCT within the Paediatric Research in Emergency Departments International Collaborative (PREDICT).

Methods: A retrospective analysis of ED medical records of children less than 18 years diagnosed with Bell's palsy between 1 January, 2012 and 31 December, 2013 was performed. Potential participants were identified from ED information systems using Bell's palsy related search terms. Repeat presentations during the same illness were excluded but relapses were not. Data on presentation, diagnosis and management were entered into an online data base (REDCap).

Results: Three hundred and twenty-three presentations were included from 14 PREDICT sites. Mean age at presentation was 9.0 (SD 5.0) years with 184 (57.0%) females. Most (238, 73.7%) presented to ED within 72 h of symptoms, 168 (52.0%) had seen a doctor prior. In ED, 218 (67.5%) were treated with steroids. Prednisolone was usually prescribed for 9 days at around 1 mg/kg/day, with tapering in 35.7%.

Conclusion: Treatment of Bell's palsy in children presenting to Australasian EDs is varied. Prednisolone is commonly used in Australasian EDs, despite lack of high-level paediatric evidence. The study findings confirm the feasibility of an RCT of prednisolone for Bell's palsy in children.

Item ID: 50471
Item Type: Article (Research - C1)
ISSN: 1440-1754
Keywords: Bell's palsy, child, facial palsy, prednisolone
Funders: National Health and Medical Research Council (NHMRC), Murdoch Children's Research Institute (MCRI), Victorian Government's Operational Infrastructure Support Program, Royal Children's Hospital Foundation, Health Research Council of New Zealand (HRCNZ)
Projects and Grants: NHMRC grant GNT1058560, HRCNZ HRC13/556
Date Deposited: 20 Sep 2017 09:24
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3209 Neurosciences > 320905 Neurology and neuromuscular diseases @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920111 Nervous System and Disorders @ 100%
Downloads: Total: 1
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page