Preparation of microparticles through co-flowing of partially miscible liquids

He, Yinghe, Battat, Sarah, Fan, Jing, Abbaspourrad, Alireza, and Weitz, David A. (2017) Preparation of microparticles through co-flowing of partially miscible liquids. Chemical Engineering Journal, 320. pp. 144-150.

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Abstract

Monodisperse microparticles find applications in a wide range of areas. Generation of such particles of several microns in size at a large scale is a difficult task. This paper reports a proof of concept using a microfluidic device that coaxially flows partially miscible liquids for the production of microparticles. The approach makes use of both the physical forces of the process and the chemical properties of the liquid systems that allows for careful control of the mixing and droplet formation processes. Initial results show that, with this approach, particles with a reasonably narrow size distribution can be produced and liquid miscibility can be used as an additional avenue to manipulate the mean particle size and morphology.

Item ID: 50339
Item Type: Article (Research - C1)
ISSN: 1873-3212
Keywords: microparticles, partially miscible liquids, controlled mixing
Date Deposited: 20 Sep 2017 08:02
FoR Codes: 09 ENGINEERING > 0904 Chemical Engineering > 090406 Powder and Particle Technology @ 70%
09 ENGINEERING > 0904 Chemical Engineering > 090403 Chemical Engineering Design @ 30%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970109 Expanding Knowledge in Engineering @ 100%
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