Elevated fasting glucose and albuminuria may be a marker for all-cause mortality in Indigenous adults in North Queensland - a follow up study, 1998-2006

Li, Ming, and McDermott, Robyn (2017) Elevated fasting glucose and albuminuria may be a marker for all-cause mortality in Indigenous adults in North Queensland - a follow up study, 1998-2006. Journal of Diabetes and its Complications, 31 (4). pp. 708-714.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: https://doi.org/10.1016/j.jdiacomp.2016....
 
1
1


Abstract

Aims: To document risk factors of all-cause mortality in a cohort of indigenous Australians from 23 communities of North Queensland during 1998-2006.

Methods: Among 2787 indigenous adults, baseline weight, waist circumference, blood pressure, fasting glucose, lipids, gamma-glutamyl transferase, urine albumin creatinine ratio, smoking, alcohol intake and physical activity were measured in 1998-2000. Deaths were ascertained from State Registry of Deaths, hospitalization and clinical records till 2006. Mortality risk factors were assessed using a Cox proportional-hazards model.

Results: The standardized all-cause mortality rate was 23.2/1000 person-years (95% CI 203-263/1000 pys). After adjusting for age, sex, and ethnicity, baseline plasm fasting glucose > = 5.5 mmol/L was associated with a 50% increased risk of death (HR 1.5, 95% Cl 1.2-2.0). Albuminuria was associated with all-cause mortality with a hazards ratio of 1.4 for microalbuminuria (95% CI 1.0-1.9) and 2.6 (95% CI 1.8-3.7) for macroalbuminuria. Gamma-glutamyl transferase > = 50 IU was associated with an increased risk of all-cause mortality by 40% (95% CI 1.04-1.8).

Conclusions: Fasting glycaemia, albuminuria, and gamma-glutamyl transferase, may be a marker for all-cause mortality within this cohort.

Item ID: 50313
Item Type: Article (Research - C1)
ISSN: 1873-460X
Keywords: all-cause mortality, Indigenous Australians, fasting blood glucose, albuminuria, gamma-glutamyl transferase
Funders: National Health and Medical Research Council (NHMRC), Department of Health and Ageing
Projects and Grants: NHMRC grant number 279402
Date Deposited: 20 Sep 2017 07:52
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111701 Aboriginal and Torres Strait Islander Health @ 60%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110399 Clinical Sciences not elsewhere classified @ 40%
SEO Codes: 92 HEALTH > 9203 Indigenous Health > 920301 Aboriginal and Torres Strait Islander Health - Determinants of Health @ 60%
92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920104 Diabetes @ 40%
Downloads: Total: 1
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page