Review: capripoxvirus diseases: current status and opportunities for control

Tuppurainen, E.S.M., Venter, E.H., Shisler, J.L., Gari, G., Mekonnen, G.A., Juleff, N., Lyons, N.A., De Clercq, K., Upton, C., Bowden, T.R., Babiuk, S., and Babiuk, L.A. (2017) Review: capripoxvirus diseases: current status and opportunities for control. Transboundary and Emerging Diseases, 64 (3). pp. 729-745.

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Abstract

Lumpy skin disease, sheeppox and goatpox are high-impact diseases of domestic ruminants with a devastating effect on cattle, sheep and goat farming industries in endemic regions. In this article, we review the current geographical distribution,economic impact of an outbreak, epidemiology, transmission and immunity of capripoxvirus. The special focus of the article is to scrutinize the use of currently available vaccines to investigate the resource needs and challenges that will have to be overcome to improve disease control and eradication, and progress on the development of safer and more effective vaccines. In addition, field evaluation of the efficacy of the vaccines and the genomic database available for poxviruses are discussed.

Item ID: 49284
Item Type: Article (Research - C1)
ISSN: 1865-1682
Keywords: lumpy skin disease; sheeppox; goatpox; immunity; control; vaccines
Additional Information:

© 2015 The Authors. Transboundary and Emerging Diseases Published by Blackwell Verlag GmbH • Transboundary and Emerging Diseases. 64 (2017) 729–745. This is an open access article under the terms of the Creative Commons Attribution License, (https://creativecommons.org/licenses/by/4.0/) which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Funders: Bill and Melinda Gates Foundation (BMGF)
Projects and Grants: BMGF OPP1126866
Date Deposited: 23 Jun 2017 02:09
FoR Codes: 07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070712 Veterinary Virology @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences @ 100%
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