Temporal trends of leprosy in a Brazilian state capital in Northeast Brazil: epidemiology and analysis by joinpoints, 2001 to 2012

Brito, Aline Lima, Monteiro, Lorena Dias, Ramos, Alberto Novaes, Heukelbach, Jorg, and Alencar, Carlos Alencar (2016) Temporal trends of leprosy in a Brazilian state capital in Northeast Brazil: epidemiology and analysis by joinpoints, 2001 to 2012. Revista Brasileira de Epidemiologia, 19 (1). pp. 194-204.

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Abstract

The objective of this study was to characterize epidemiological and temporal trends of leprosy in the city of Fortaleza, Ceará, Brazil, from 2001 to 2012. A total of 9,658 new cases were reported. Their temporal trend was analyzed by the jointpoint regression model. The overall detection rate showed a declining trend, with annual percent change (APC) of ‑4.0 and 95% confidence interval (95%CI) ‑5.6 – ‑2.3. The detection rate in children under 15 years of age (APC = ‑1.4; 95%CI ‑5.4 – 2.8) and the detection rate of disability grade 2 (APC = ‑0.8; 95%CI ‑4.5 – 3.1) were stable. The proportion of female patients was descending (APC = ‑1,5; 95%CI ‑2.3 – ‑0.8). The proportion of multibacillary cases from 2005 to 2012 (APC = 1.4; 95%CI 0.6 – 2.3) and among them, lepromatous cases from 2004 to 2012 (APC = 6.0; 95%CI 3.4 – 8.6) were increasing. There was stability in the proportion of cases with grade 1 (APC = 1.4; 95%CI ‑0.9 – 3.7) and grade 2 disability (APC = 3.7; 95%CI ‑0.1 – 7.8). Despite the trend towards a reduction in detection, the disease transmission persists in the city. The data also suggest late diagnosis.

Item ID: 49255
Item Type: Article (Research - C1)
ISSN: 1980-5497
Keywords: Brazil, epidemiology, leprosy, communicable diseases, nglected diseases, incidence
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Date Deposited: 08 Jun 2017 02:07
FoR Codes: 42 HEALTH SCIENCES > 4202 Epidemiology > 420205 Epidemiological modelling @ 50%
42 HEALTH SCIENCES > 4206 Public health > 420699 Public health not elsewhere classified @ 50%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920499 Public Health (excl. Specific Population Health) not elsewhere classified @ 100%
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