Construction of fluoride containing PLLA nanofiber scaffold for bone regeneration

Ye, Qingsong, Xu, Jia, He, Yan, and Sandham, Andrew (2014) Construction of fluoride containing PLLA nanofiber scaffold for bone regeneration. Annals of the Royal Australasian College of Dental Surgeons, 22. pp. 71-73.

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In this study, a novel material, fluoride-containing Poly (L-lactic acid) (PLLA) nanofibre scaffold was successfully constructed through electrospinning process. Scanning electron microscopy (SEM) image showed that the morphology of the fibres was uniform and smooth, and the average diameter of the fibres was about 300 nm. Transmission electron microscopy (TEM) proved that a lot of calcium fluoride (CaF2) nanoparticles with an average diameter of about 50 nm were well dispersed in the PLLA fibre matrix. Fluoride is one of the few inorganic ions which are able to stimulate osteoblasts (OB). This novel material seems to be a promising scaffold for bone tissue engineering.

Item ID: 48972
Item Type: Article (Research - C1)
ISSN: 0158-1570
Keywords: electrospinning; fluoride; nanofibre; PLLA; tissue engineering
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Funders: DECRE, James Cook University (JCU), Australian Research Council (ARC)
Projects and Grants: DECRA DE1201016, JCU Rising Star Grant
Date Deposited: 02 Aug 2017 04:52
FoR Codes: 09 ENGINEERING > 0903 Biomedical Engineering > 090301 Biomaterials @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
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