Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: a large population based cross sectional study

Qin, Xiao-Di, Qian, Zhengmin, Vaughn, Michael, Trevathan, Edwin, Emo, Brett, Paul, Gunther, Ren, Wan-Hui, Hao, Yuan-Tao, and Dong, Guang-Hui (2015) Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: a large population based cross sectional study. Science of the Total Environment, 529. pp. 243-248.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: http://dx.doi.org/10.1016/j.scitotenv.20...
23


Abstract

Background: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China.

Methods: We studied 24,845 Chinese adults, aged 18 to 74 years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25—29.9 and ? 30 kg/m2, respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006—2008) average concentrations of particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), and ozone (O3) were measured by fixed monitoring stations. All the participants lived within 1 km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates.

Results: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15—1.47 for stroke, 1.33—1.59 for CVDs), less strong in overweight subjects (OR 1.22—1.35 for stroke, 1.07—1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98—1.01 for stroke, 0.93—1.15 for CVDs). When stratified by gender, these interactions were significant only in women.

Conclusions: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality of BMI relative to exposure and onset of disease.

Item ID: 48188
Item Type: Article (Research - C1)
ISSN: 1879-1026
Keywords: air pollution, obesity, cardiovascular disease, stroke, China
Funders: China Environmental Protection Foundation (CEPF), Guangdong Province Natural Science Foundation (GPNSF)
Projects and Grants: CEPF (CEPF2008-123-1-5), GPNSF (1431520600005)
Date Deposited: 17 Jul 2017 00:48
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111705 Environmental and Occupational Health and Safety @ 80%
11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 20%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920405 Environmental Health @ 100%
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page