Identification of two distinct bovine parainfluenza virus type 3 genotypes

Horwood, Paul Francis, Gravel, Jennifer Lillian, and Mahony, Timothy John (2008) Identification of two distinct bovine parainfluenza virus type 3 genotypes. Journal of General Virology, 89 (7). pp. 1643-1648.

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The partial gene sequencing of the matrix (M) protein from seven clinical isolates of bovine parainfluenza virus type 3 (BPIV-3), and the complete sequencing of a representative isolate (Q5592) was completed in this study. Nucleotide sequence analysis was initiated because of the failure of in-house BPIV-3 RT-PCR methods to yield expected products for four of the isolates. Phylogenetic reconstructions based on the nucleotide sequences for the M-protein and the entire genome, using all of the available BPIV-3 nucleotide sequences, demonstrated that there were two distinct BPIV-3 genotypes (BPIV-3a and BPIV-3b). These newly identified genotypes have implications for the development of BPIV-3 molecular detection methods and may also impact on BPIV-3 vaccine formulations.

Item ID: 47642
Item Type: Article (Research - C1)
ISSN: 1465-2099
Funders: Meat and Livestock Australia (MLA)
Projects and Grants: MLA grant FLOT.224
Date Deposited: 08 Mar 2017 21:24
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 100%
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