Zoledronic acid effects wound healing and angiogenesis resulting in BRONJ: an in vitro and in vivo study

Sharma, D., Hamlet, S., Petcu, E., and Ivanovski, S. (2016) Zoledronic acid effects wound healing and angiogenesis resulting in BRONJ: an in vitro and in vivo study. Australian Dental Journal, 61 (4). s29-s29.

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Abstract

[Extract] Recent literature suggests that suppressed angiogenesis contributes significantly to the pathogenesis of bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) by effecting local vasculature. This in vitro and in vivo study examined the mechanisms by which the anti-angiogenic properties of BP's could lead to the occurrence of BRONJ lesions.

Item ID: 47568
Item Type: Article (Abstract)
ISSN: 1834-7819
Additional Information:

The findings of this research were presented at the Biennial Scientific Conference of the Australian Society of Periodontology, Brisbane, March 2016 where it was awarded the 'Best Poster Presentation'.

Funders: Australian Dental Research Foundation (ADRF)
Projects and Grants: ADRF grant no. 86-2014
Date Deposited: 14 Mar 2017 05:06
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110599 Dentistry not elsewhere classified @ 25%
11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110509 Special Needs Dentistry @ 50%
10 TECHNOLOGY > 1004 Medical Biotechnology > 100404 Regenerative Medicine (incl Stem Cells and Tissue Engineering) @ 25%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920113 Oro-Dental Disorders @ 75%
92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920199 Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified @ 25%
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