Yeshi, Karma, Yangdon, Pema, Kashyap, Shakuli, and Wangchuk, Phurpa (2017) Antioxidant activity and the polyphenolic and flavonoid contents of five high altitude medicinal plants used in Bhutanese Sowa rigpa medicine. Journal of Biologically Active Products from Nature, 7 (1). pp. 18-26.

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Abstract

In this work, total phenolic and flavonoid contents and antioxidant activities in methanol and aqueous extracts of five-high altitude medicinal plants namely Aconogonon tortuosum, Thlaspi arvense, Erysimum bhutanicum, Thalictrum chelidonii and Aletris pauciflora were studied for the first time from Bhutan. Antioxidant activities were investigated using DPPH radical scavenging activity (DRSA), ferric reducing antioxidant power (FRAP), superoxide dismutase (SOD) and catalase (CAT) assays. Significant level of phenolics and flavonoids were found in all medicinal herbs. Among the five plants studied, aqueous extract of Thalictrum chelidonii and methanol extract of Erysimum bhutanicum showed best free radical scavenging activity. Both aqueous and methanol extracts of Aconogonon tortuosum showed strong ferric reducing antioxidant power. The results indicate that all five medicinal herbs could be potential sources of natural antioxidant compounds and could help boost the immune system of patients.

Item ID:	47539
Item Type:	Article (Research - C1)
ISSN:	2231-1874
Keywords:	antioxidant, high altitude medicinal plants, total phenolic content, total flavonoid content, Sowa rigpa
Funders:	Nehru-Wangchuck Scholarship 2014
Date Deposited:	07 Mar 2017 00:11
FoR Codes:	34 CHEMICAL SCIENCES > 3405 Organic chemistry > 340502 Natural products and bioactive compounds @ 40% 34 CHEMICAL SCIENCES > 3404 Medicinal and biomolecular chemistry > 340401 Biologically active molecules @ 40% 34 CHEMICAL SCIENCES > 3405 Organic chemistry > 340501 Free radical chemistry @ 20%
SEO Codes:	86 MANUFACTURING > 8608 Human Pharmaceutical Products > 860801 Human Biological Preventatives (e.g. Vaccines) @ 80% 82 PLANT PRODUCTION AND PLANT PRIMARY PRODUCTS > 8299 Other Plant Production and Plant Primary Products > 829999 Plant Production and Plant Primary Products not elsewhere classified @ 10% 92 HEALTH > 9202 Health and Support Services > 920299 Health and Support Services not elsewhere classified @ 10%
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