Verapamil treatment in severe Chironex fleckeri stings

Isbister, Geoffrey K., Ramasamy, Sharmaine, Seymour, Jamie E., and Hodgson, Wayne C. (2004) Verapamil treatment in severe Chironex fleckeri stings. Toxicon, 44 (8). pp. 819-820.

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[Extract] We thank Burnett and Calton for their interest in our work on Chironex fleckeri venom. However, we have significant concerns that they have focussed on the use of verapamil, and not discussed this in relation to the value of antivenom and magnesium. Importantly, the recommendation of verapamil treatment for severe jellyfish stings in humans, based on animal experiments, cannot be made lightly considering the severe adverse effects of verapamil in patients with cardiac decompensation. We have demonstrated in our study that verapamil worsened the outcome when given in conjunction with antivenom.

Item ID: 45680
Item Type: Article (Commentary)
ISSN: 1879-3150
Date Deposited: 12 Sep 2016 23:13
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970111 Expanding Knowledge in the Medical and Health Sciences @ 100%
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