Effects of long-term occlusal hypofunction and its recovery on the morphogenesis of molar roots and the periodontium in rats

Motokawa, Masahide, Terao, Akiko, Karadeniz, Ersan I., Kaku, Masato, Kawata, Toshitsugu, Matsuda, Yayoi, Gonzales, Carmen, Darendeliler, M. Ali, and Tanne, Kazuo (2013) Effects of long-term occlusal hypofunction and its recovery on the morphogenesis of molar roots and the periodontium in rats. Angle Orthodontist, 83 (4). pp. 597-604.

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Abstract

Objectives: To investigate the effects of long-term, artificially created, hypofunctional occlusion and its recovery on the morphology of rat molar roots.

Material and Methods: Eighteen 5-week-old Wistar-strain male rats were randomly divided according to their periodontal conditions into normal, hypofunctional, and recovery groups (n  =  6 in each). In the experimental hypofunctional and recovery groups, a bite-raising appliance was set to produce hypofunction at the molar region. All groups were analyzed at 16 weeks of age using three-dimensional micro-computed tomography. Root length, width, and area as well as the thickness and the area of the periodontal ligament (PDL) space of the maxillary first molar were calculated.

Results: Roots were longer and narrower in the hypofunctional group than in the control group. The mesial root in particular showed a dramatic change. Root area also decreased significantly in the hypofunctional group compared to the other groups. Moreover, the PDL thickness and area decreased significantly in the hypofunctional group compared to the control group, but increased in the recovery group compared to the hypofunctional group.

Conclusions: These findings suggest that root size and PDL structure may be reduced due to disuse atrophy resulting from a defect in occlusal function, but may be recovered following a gain of occlusal stimuli.

Item ID: 45156
Item Type: Article (Research - C1)
ISSN: 1945-7103
Keywords: hypofunctional occlusion; occlusal recovery condition; normal occlusion; root morphology; PDL space
Funders: Ministry of Education, Culture, Sports, Science and Technology of Japan (MECSST)
Projects and Grants: MECSST Grant-in-Aid for Basic research (C) (No. 22592285)
Date Deposited: 17 Aug 2016 01:05
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110506 Orthodontics and Dentofacial Orthopaedics @ 70%
11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110508 Periodontics @ 20%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110320 Radiology and Organ Imaging @ 10%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920113 Oro-Dental Disorders @ 50%
92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920402 Dental Health @ 50%
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