An in vivo 3D micro-CT evaluation of tooth movement after the application of different force magnitudes in rat molar

Gonzales, Carmen, Hotokezaka, Hitoshi, Arai, Yoshinori, Ninomiya, Tadashi, Tominaga, Junya, Jang, Insan, Hotokezaka, Yuka, Tanaka, Motohiro, and Yoshida, Noriaki (2009) An in vivo 3D micro-CT evaluation of tooth movement after the application of different force magnitudes in rat molar. Angle Orthodontist, 79 (4). pp. 703-714.

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Objective: To investigate the precise longitudinal change in the periodontal ligament (PDL) space width and three-dimensional tooth movement with continuous-force magnitudes in living rats.

Materials and Methods: Using nickel-titanium closed-coil springs for 28 days, 10-, 25-, 50-,and 100-g mesial force was applied to the maxillary left first molars. Micro-CT was taken in the same rat at 0, 1, 2, 3, 10, 14, and 28 days. The width of the PDL was measured in the pressure and tension sides from 0 to 3 days. Angular and linear measurements were used to evaluate molar position at day 0, 10, 14, and 28. The finite element model (FEM) was constructed to evaluate the initial stress distribution, molar displacement, and center of rotation of the molar.

Results: The initial evaluation of PDL width showed no statistical differences among different force magnitudes. Tooth movement was registered 1 hour after force application and gradually increased with time. From day 10, greater tooth movement was observed when 10 g of force was applied. The FEM showed that the center of rotation in the molar is located in the center of five roots at the apical third of the molar roots.

Conclusion: The rat's molar movement mainly consists of mesial tipping, extrusion of distal roots, intrusion of mesial root, palatal inclination, and mesial rotation. Although the initial tooth movement after the application of different force magnitudes until day 3 was not remarkably different, 10 g of force produced more tooth movement compared with heavier forces at day 28.

Item ID: 45150
Item Type: Article (Research - C1)
ISSN: 1945-7103
Keywords: tooth movement; in vivo micro-CT; FEM; rat molar; time lapse; superimposition
Funders: Ministry of Education, Science, Sports and Culture of Japan
Date Deposited: 14 Sep 2016 01:48
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110506 Orthodontics and Dentofacial Orthopaedics @ 80%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110320 Radiology and Organ Imaging @ 20%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920113 Oro-Dental Disorders @ 50%
92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920402 Dental Health @ 50%
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