Primary tuberculous gingival enlargement: a rare entity

Karthikeyan, Bangalore Varadhan, Pradeep, Avani Raju, and Sharma, C.G. Dileep (2006) Primary tuberculous gingival enlargement: a rare entity. Journal of the Canadian Dental Association, 72 (7). pp. 645-648.

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With the advent of effective drug therapy, tuberculous lesions of the oral cavity have become so rare that they are frequently forgotten. Primary gingival tuberculosis is extremely rare and usually manifests as ulcer. We report the first case of primary tuberculosis manifesting as gingival enlargement, which was the only presenting sign of tuberculosis. Diagnosis was based on histopathology (hematoxin and eosin staining), complete blood count, polymerase chain reaction assay and immunologic investigation with the detection of antibodies against Mycobacterium tuberculosis. The possibility of gingival enlargement due to drugs, leukemia, fungus and sarcoidosis was ruled out. Antituberculous therapy over 6 months was followed by surgical excision of the residual enlargement under local anesthesia. After 1-year follow-up there was no recurrence of the disease. This case emphasizes the need for dentists to include tuberculosis in the differential diagnosis of gingival enlargement so that they may play a role in its early detection.

Item ID: 44290
Item Type: Article (Research - C1)
ISSN: 1488-2159
Keywords: bacterial DNA; tuberculostatic agent, article; case report; child; differential diagnosis; female; gingiva hypertrophy; gingivoplasty; human; tuberculosis; antitubercular agents; child; diagnosis; differential; DNA; bacterial; female; gingival hypertrophy; gingivoplasty; humans; tuberculosis, oral
Date Deposited: 01 Nov 2016 04:31
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110505 Oral Medicine and Pathology @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110508 Periodontics @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920113 Oro-Dental Disorders @ 100%
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