Herpesviruses in chronic and aggressive periodontitis patients in an Indian population

Bilichodmath, Shivaprasad, Mangalekar, Sachin B. , Sharma, Dileep C.G., Prabhakar, Ashok K. , Reddy, Sridhar B. , Kalburgi, Nagaraj B. , Patil, Sudhir R. , and Bhat, Kishore (2009) Herpesviruses in chronic and aggressive periodontitis patients in an Indian population. Journal of Oral Science, 51 (1). pp. 79-86.

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Many recent studies have assessed the prevalence and role of herpesviruses in the etiopathogenesis of periodontal diseases, which has led to the realization of intricate interactions between viruses and bacteria within periodontal pockets. It has also been shown that the occurrence of herpesviruses may vary depending upon the age of the patient and the race of the population studied. Thus, the present study aimed at detecting herpes simplex virus type 1 and 2 (HSV 1 and 2), Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) in periodontal pockets of Indian patients with chronic and aggressive periodontitis. Subgingival plaque samples (n = 33) were collected from 19 randomly chosen chronic periodontitis and 14 aggressive periodontitis patients. Herpesviruses were detected using multiplex polymerase chain reaction technique. Chronic periodontitis patients revealed presence of HSV-1 in 19 (100) samples, HSV-2 in 3 (15.7), EBV in 15 (78.9) and HCMV in 5 (26.31) samples. Samples from aggressive periodontitis patients showed the presence of HSV-1 in 8 (57.14), EBV in 4 (28.57) and HCMV in 1 (7.14), whereas HSV-2 was not detected in any specimen. In this population, herpesviruses were found more frequently in chronic periodontitis than in aggressive periodontitis patients and their prevalence may vary according to the age and race of the patient.

Item ID: 44282
Item Type: Article (Research - C1)
ISSN: 1880-4926
Keywords: adolescent; adult; age; article; child; chronic periodontitis; classification; Cytomegalovirus; Epstein Barr virus; female; Herpes simplex virus 1; Herpes simplex virus 2; Herpes virus; Herpes virus infection; human; India; isolation and purification; male; middle aged; periodontal disease; periodontitis; tooth plaque; virology, Adolescent; Adult; Age Factors; Aggressive Periodontitis; Child; Chronic Periodontitis; Cytomegalovirus; Dental Plaque; Female; Herpesviridae; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 4, Human; Humans; India; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Young Adult
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Date Deposited: 16 Jun 2016 01:54
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110508 Periodontics @ 80%
03 CHEMICAL SCIENCES > 0304 Medicinal and Biomolecular Chemistry > 030405 Molecular Medicine @ 20%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920113 Oro-Dental Disorders @ 100%
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