Surrogate markers of abdominal aortic aneurysm progression

Wanhainen, Anders, Mani, Kevin, and Golledge, Jonathan (2016) Surrogate markers of abdominal aortic aneurysm progression. Arteriosclerosis, Thrombosis and Vascular Biology, 36 (2). pp. 236-244.

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Abstract

The natural course of many abdominal aortic aneurysms (AAA) is to gradually expand and eventually rupture and monitoring the disease progression is essential to their management. In this publication, we review surrogate markers of AAA progression. AAA diameter remains the most widely used and important marker of AAA growth. Standardized reporting of reproducible methods of measuring AAA diameter is essential. Newer imaging assessments, such as volume measurements, biomechanical analyses, and functional and molecular imaging, as well as circulating biomarkers, have potential to add important information about AAA progression. Currently, however, there is insufficient evidence to recommend their routine use in clinical practice.

Item ID: 43336
Item Type: Article (Research - C1)
ISSN: 1524-4636
Keywords: aortic aneurysm, abdominal, biomarkers, magnetic resonance imaging, molecular imaging, ultrasonography
Date Deposited: 02 Mar 2016 07:39
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
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