Diagnosis of latent tuberculosis infection among HIV-infected clients in Far North Queensland: use of an interferon-gamma release assay

Lyne, Katrina, Downing, Sandra, and Russell, Darren (2013) Diagnosis of latent tuberculosis infection among HIV-infected clients in Far North Queensland: use of an interferon-gamma release assay. Sexual Health, 10 (4). pp. 389-390.

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Abstract

Latent Mycobacterium tuberculosis infection is a significant risk for those infected with HIV. We examined the use of an interferon-gamma release assay for the diagnosis of latent tuberculosis among HIV-infected clients attending two sexual health services in Far North Queensland. Of 240 clients tested, 19 returned a positive result (7.9%, 95% confidence interval (CI): 4.5–11.3%) and three were indeterminate (1.3%, 95% CI: –0.2%–2.7%). Low CD4 count was found to be significantly associated with an indeterminate test result (P = 0.004). However, we found no significant association between test results and client demographics, self-reported prior tuberculosis infection, Bacille Calmette-Guérin vaccine status or selected tuberculosis risk factors (P-values = 0.2–0.9).

Item ID: 43092
Item Type: Article (Research - C1)
ISSN: 1449-8987
Keywords: diagnosis, interferon-gamma release tests, Mycobacterium tuberculosis
Date Deposited: 09 Sep 2016 02:06
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111717 Primary Health Care @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 100%
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