Serum IP-10 in the diagnosis of latent and active tuberculosis

Clifford, Vanessa, Tebruegge, Marc, Zufferey, Christel, Germano, Susie, Denholm, Justin, Street, Alan, McBryde, Emma, Eisen, Damon, and Curtis, Nigel (2015) Serum IP-10 in the diagnosis of latent and active tuberculosis. Journal of Infection, 71 (6). pp. 696-698.

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Abstract

We read with interest the recent article by Wergeland et al., reporting that serum interferon-gamma inducible protein 10 (IP-10) may be a useful biomarker for differentiating between active tuberculosis (TB) and latent TB infection (LTBI), as well as for monitoring the effectiveness of anti-tuberculous therapy.1 However, a key limitation of this study was the absence of a 'sick control' group of patients with respiratory tract infections. Prompted by this finding, we analysed data from our ongoing study investigating novel biomarkers of active and latent TB.

Item ID: 42206
Item Type: Article (Commentary)
ISSN: 1532-2742
Keywords: tuberculosis; IP-10; latent TB; active TB; diagnostics
Funders: John Burge Trust Fund (JBTF)
Projects and Grants: JBTF 1203
Date Deposited: 26 Jun 2016 23:53
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 40%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111706 Epidemiology @ 40%
16 STUDIES IN HUMAN SOCIETY > 1605 Policy and Administration > 160508 Health Policy @ 20%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 50%
92 HEALTH > 9202 Health and Support Services > 920207 Health Policy Evaluation @ 50%
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