Suicide rates and antidepressant prescribing: a casual or causal relationship

Baune, Bernhard, and Hay, Phillipa (2006) Suicide rates and antidepressant prescribing: a casual or causal relationship. PLoS Medicine, 3 (6). pp. 734-735.

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Abstract

In an ecological study in this issue of PLoS Medicine, Milane and colleagues found a temporal association between prescription of specific serotonin reuptake inhibitor (SSRI) antidepressants and suicide rates in the United States [1]. Their study addresses a subject of great public health importance and clinical interest. The researchers asked the question: was the use of antidepressants associated with a change in suicide rates in the general population of the United States between 1988 and 2002? There were two underlying hypotheses: (1) antidepressants can trigger suicide and subsequently increase suicide rates, and (2) through the treatment of depression with antidepressants, suicide rates decline over time.

Item ID: 4120
Item Type: Article (Refereed Research - C1)
Keywords: suicide rates; depression; drug therapy; Fluoxetine; adverse effects
Additional Information:

© 2006 Baune and Hay. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ISSN: 1549-1676
Date Deposited: 30 Oct 2009 01:55
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111714 Mental Health @ 34%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110319 Psychiatry (incl Psychotherapy) @ 33%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111799 Public Health and Health Services not elsewhere classified @ 33%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920410 Mental Health @ 51%
92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 49%
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