Chenoweth, Peter, and McPherson, Francoise J. (2014) Genetic aspects of male reproduction. In: Chenoweth, Peter J., and Lorton, Steven P., (eds.) Animal Andrology: theories and applications. CABI, Wallingford, UK, pp. 144-174.

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Abstract

[Extract] Genetic disorders are those caused by abnormalities or defects in genes or chromosomes. Although many genetic disorders are transmitted via parental genes, others are a result of DNA changes or mutations that are not necessarily heritable. Congenital disorders, in contrast, are those that exist at birth (though they may become first evident either earlier or later). These may be caused by a number of factors, including genetic disorders. Howeve1~ they can also be caused by developmental anomalies, infections, the uterine environment, and metabolic, nutritional and toxic factors, in addition to joint genetic environmental and epigenetic influences. Those that are proven to be heritable may be transmitted via single gene (or Mendelian) inheritance, or via complex mechanisms that may involve multiple genes as well as environmental effects. For examples of conditions subject to the former mode of inheritance in cattle, readers are referred to the web site (http://dga.jouy.inra.fr/lgbc/mic2000/).

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