Gadda, Rohit B., Pai, Keerthilatha M., and Sholapurkar, Amar A. (2010) Non-syndromic oligodontia in permanent dentition of monozygotic twins: report of a rare case. The Journal of Contemporary Dental Practice, 11 (2). pp. 1-6.

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Abstract

Aim: To report a case of non-syndromic oligodontia involving 26 permanent teeth in monozygotic twin sisters and to discuss the possible genetic etiology, inheritance pattern and associated dental anomalies of this condition.

Background: Hypodontia constitutes one of the most common developmental anomalies in humans and is defined as developmental absence of one or more teeth with reported prevalence of 1.6 to 9.6% in the permanent dentition. Oligodontia is defined as agenesis of six or more teeth excluding third molars.

Case Report: This article describes a case of non-syndromic oligodontia involving 26 permanent teeth in monozygotic twin sisters. The twins had positive family history of hypodontia in their paternal grandmother, parental consanguinity (first cousin) and similarity in pattern of oligodontia. Root formation of permanent maxillary first molars and central incisors was delayed in both the twins.

Summary: This article reports a case of non-syndromic oligodontia in permanent dentition of monozygotic twins. Possible genetic etiology, inheritance pattern and associated dental anomalies are discussed.

Clinical Significance: Strong genetic link associated with oligodontia help the dentist to know the possibility of its occurrence in other family members and in future generations.

Item ID:	39809
Item Type:	Article (Case Study)
ISSN:	1526-3711
Keywords:	oligodontia; monozygotic twins; hypodontia; genetic consanguinity
Date Deposited:	26 Aug 2015 01:22
FoR Codes:	11 MEDICAL AND HEALTH SCIENCES > 1105 Dentistry > 110505 Oral Medicine and Pathology @ 100%
SEO Codes:	92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920402 Dental Health @ 100%
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