Using samples to estimate the sensitivity and specificity of a surveillance process

McBryde, Emma S., Kelly, Heath, Marshall, Caroline, Russo, Philip L., McElwain, D.L. Sean, and Pettitt, Anthony N. (2008) Using samples to estimate the sensitivity and specificity of a surveillance process. Infection Control and Hospital Epidemiology, 29 (6). pp. 559-563.

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Abstract

Determining sensitivity and specificity of a postoperative infection surveillance process is a difficult undertaking. Because postoperative infections are rare, vast numbers of negative results exist, and it is often not reasonable to assess them all. This study gives a methodological framework for estimating sensitivity and specificity by taking only a small sample of the number of patients who test negative and comparing their findings to the reference or "gold standard" rather than comparing the findings of all patients to the gold standard. It provides a formula for deriving confidence intervals for these estimates and a guide to minimum requirements for sampling results.

Item ID: 39783
Item Type: Article (Research - C1)
ISSN: 1559-6834
Funders: National Health and Medical Research Council (NHMRC), Centre for Clinical Research Excellence in Infectious Diseases
Projects and Grants: NHMRC Capacity Building Grant 358424
Date Deposited: 08 Oct 2015 00:02
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 40%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111706 Epidemiology @ 40%
16 STUDIES IN HUMAN SOCIETY > 1605 Policy and Administration > 160508 Health Policy @ 20%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 60%
92 HEALTH > 9203 Indigenous Health > 920309 Pacific Peoples Health - Health System Performance (incl. Effectiveness of Interventions) @ 20%
92 HEALTH > 9202 Health and Support Services > 920207 Health Policy Evaluation @ 20%
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