An association between aspirin use in human cases of infective endocarditis and reduced systemic embolism is shown in meta-analysis of observational studies

Eisen, Damon P., and McBryde, Emma S. (2015) An association between aspirin use in human cases of infective endocarditis and reduced systemic embolism is shown in meta-analysis of observational studies. Journal of Infectious Diseases, 212 (4). pp. 673-674.

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Abstract

[Extract] Animal studies such as published recently in this journal [1] show benefits of antiplatelet agents in experimental models of Staphylococcus aureus infective endocarditis (IE). It is, therefore, important to consider how these experimental data translate into clinical practice. A number of human studies have considered this area, concentrating almost exclusively on long-term aspirin usage. We have performed a meta-analysis of these 9 published studies [2–10] to assess whether the data may provide a basis for future trials and possibly change Infectious Diseases Society of America guidelines that recommend that aspirin should not be used in IE.

Item ID: 39730
Item Type: Article (Commentary)
ISSN: 1537-6613
Date Deposited: 08 Sep 2015 01:54
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 40%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111706 Epidemiology @ 40%
16 STUDIES IN HUMAN SOCIETY > 1605 Policy and Administration > 160508 Health Policy @ 20%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 60%
92 HEALTH > 9203 Indigenous Health > 920309 Pacific Peoples Health - Health System Performance (incl. Effectiveness of Interventions) @ 20%
92 HEALTH > 9202 Health and Support Services > 920207 Health Policy Evaluation @ 20%
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