Anthropometric measurements, adipokines and abdominal aortic calcification

Parr, Adam Franklin, and Golledge, Jonathan (2012) Anthropometric measurements, adipokines and abdominal aortic calcification. In: Preedy, Victor R., (ed.) Handbook of Anthropometry: physical measures of human form in health and disease. Springer, New York, NY, USA, pp. 2171-2184.

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Obesity and arterial calcification are associated with increased cardiovascular morbidity and mortality. The relationship between obesity and abdominal aortic calcification has been under investigated. The majority of research has focused on the relationship between clinical anthropometric measures and aortic calcification, with mixed results. Numerous calcification measurement protocols have hindered appropriate analysis of the literature. However, recently a reproducible computed tomography method for aortic calcification quantification has been published. Similarly, many methods are available for anthropometric assessment. Clinical measures include body mass index, waist circumference, waist to hip ratio, skin fold and percent body fat. Alternatively, computed tomography can be reproducibly utilized to measure abdominal adipose diameters, area and volume.

Recently, the relationship between calcification and anthropometric measurements has been investigated by computed tomography. It was found that a measure of visceral adiposity was associated with abdominal aortic calcification. In addition, visceral adiposity was positively and negatively correlated to circulating concentrations of osteoprotegerin and leptin, respectively. This has provided a possible pathogenic mechanism for the accumulation of abdominal aortic calcification.

The aims of this chapter are two fold:

1. To outline the various anthropometric and calcification protocols currently employed for vascular research.

2. To review the current literature regarding the relationship between anthropometric measures and abdominal aortic calcification.

Item ID: 39294
Item Type: Book Chapter (Research - B1)
ISBN: 978-1-4419-1787-4
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Funders: National Health and Medical Research Council (NHMRC), National Institutes of Health (NIH)
Projects and Grants: NHMRC project grant 540403, NHMRC project grant 540404, NHMRC project grant 540405, NIH RO1 HL080010, NHMRC Practitioner Fellowship 431503
Date Deposited: 07 Nov 2016 02:55
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
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