Intestinal allergy expels hookworms: seeing is believing

Croese, John, and Speare, Richard (2006) Intestinal allergy expels hookworms: seeing is believing. Trends in Parasitology, 22 (12). pp. 547-550.

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Abstract

It is unclear how immunity limits hookworm infection. Australian researchers, using capsule and conventional gastrointestinal endoscopy in volunteers inoculated with Necator americanus, have reported that virtually all larvae reach the intestine within six weeks. Unlike the neutral response surrounding resident hookworms, newly arrived adults provoke an eosinophilic enteropathy. This allergic reaction curtails the attachment of hookworms and accompanies the passage of additional worms as they are expelled from the proximal small intestine.

Item ID: 3925
Item Type: Article (Research - C1)
ISSN: 1471-5007
Keywords: Necator americanus; hookworm; allergy; expulsion; capsule endoscopy
Date Deposited: 18 Nov 2009 01:01
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920105 Digestive System Disorders @ 100%
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