Neutrophil labeling with [(90m)Tc]-technetium stannous colloid is complement receptor 3-mediated and increases the neutrophil priming response to lipopolysaccharide
Gallagher, Hayley, Ramsay, Stuart C., Barnes, Jodie , Maggs, Jacqueline, Cassidy, Nathan, and Ketheesan, Natkunam (2006) Neutrophil labeling with [(90m)Tc]-technetium stannous colloid is complement receptor 3-mediated and increases the neutrophil priming response to lipopolysaccharide. Nuclear Medicine and Biology, 33 (3). pp. 433-439.
![[img]](https://researchonline.jcu.edu.au/style/images/fileicons/application_pdf.png) |
PDF (Published Version)
- Published Version
Restricted to Repository staff only |
Abstract
99mTc]-technetium stannous colloid (TcSnC)-labeled white cells are used to image inflammation. Neutrophil labeling with TcSnC is probably phagocytic, but the phagocytic receptor involved is not known. We hypothesised that complement receptor 3 (CR3) plays a key role. Phagocytic labeling could theoretically result in neutrophil activation or priming, affecting the behaviour of labeled cells. Fluorescence-activated cell sorter (FACS) analysis side scatter measurements can assess neutrophil activation and priming.
| Item ID: | 3915 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 0969-8051 |
| Keywords: | infection; phagocytosis; CR3; CD11b; labeled white blood cells |
| Date Deposited: | 20 Nov 2009 00:51 |
| FoR Codes: | 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 80% 11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110704 Cellular Immunology @ 20% |
| SEO Codes: | 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 80% 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 20% |
| Downloads: |
Total: 4 |
| More Statistics |
Actions (Repository Staff Only)
 |
Item Control Page |