Toxicology case of the month: oral hypoglycaemic overdose

Soderstrom, J., Murray, L., Daly, F.F.S., and Little, M. (2006) Toxicology case of the month: oral hypoglycaemic overdose. Emergency Medicine Journal, 23 (7). pp. 565-567.

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Abstract

A teenager ingests 375 mg of glipizide and 14.5 g of melformin intentionally in a small country town. She presents to the local medical facility with symptoms and signs of hypoglycaemia. Using a risk assessment based approach, the management of suiphonylurea and metformin overdose is discussed. Sulphonylurea overdose invariably results in profound hypoglycaemia that requires resuscitation with IV dextrose and the use of octreotide as an antidote. Metfonnin overdose rarely causes problems.

Item ID: 38643
Item Type: Article (Case Study)
ISSN: 1472-0213
Date Deposited: 22 Jul 2015 04:27
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111506 Toxicology (incl Clinical Toxicology) @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
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