Sundvall, Pär-Daniel, Ulleryd, Peter, and Gunnarsson, Ronny (2011) Urine culture doubtful in determining etiology of diffuse symptoms among elderly individuals [Urinodling har tveksamt värde vid beslut om antibiotikabehandling av patienter på äldreboenden]. In: [Presented at the 2011 Annual General Meeting for Physicians]. From: 2011 Annual General Meeting for Physicians, 30 November - 2 December 2011, Stockholm, Sweden.

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Abstract

Background: As many as half of elderly residents at nursing homes have asymptomatic bacteriuria. Thus it’s hard to know if a new symptom is related to findings of bacteria in urine or not. There are different opinions on the possible connection between different non-specific symptoms and urinary tract infections (UTI). Non-specific symptoms in combination with diagnostic uncertainty often lead to antibiotic treatments of uncertain value. Antibiotic overuse increases the prevalence of antibiotic resistant bacteria.

Research question: What is the relationship between bacteria in the urine and new or increased fatigue, confusion, restlessness, aggressiveness, not being herself/himself, dysuria, urgency and fever.

Methods: In this cross-sectional study symptoms were registered and voided urine specimens collected for urine cultures from 651 elderly residents in 32 nursing homes located in south-western Sweden. Correlation between bacteriuria and presence of a symptom at group level were determined using logistic regression. To estimate the clinical relevance of correlations at group level positive and negative etiological predictive values (EPV) were calculated. EPV takes into account the presence of asymptomatic bacteriuria.

Results: In this study 207/651 (32%) of urine cultures were positive. Fatigue, restlessness and confusion were the most common symptoms. Logistic regression indicated some correlations at group level. Aside from Escherichia coli in the urine and not being herself/himself present for at least one month, but less than three months, EPV indicated no clinically useful correlation between any symptoms in this study and findings of bacteriuria.

Conclusion: Urine cultures are insufficiently specific when evaluating elderly patients at nursing homes presenting with new or increased restlessness, fatigue, confusion, aggressiveness, dysuria or urgency.

Item ID:	37979
Item Type:	Conference Item (Abstract / Summary)
Related URLs:	Organisation
Date Deposited:	12 Sep 2016 00:06
FoR Codes:	11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111702 Aged Health Care @ 20% 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111717 Primary Health Care @ 30% 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111718 Residential Client Care @ 50%
SEO Codes:	92 HEALTH > 9205 Specific Population Health (excl. Indigenous Health) > 920502 Health Related to Ageing @ 30% 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920119 Urogenital System and Disorders @ 30% 92 HEALTH > 9202 Health and Support Services > 920203 Diagnostic Methods @ 40%
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