Incidence and risk of depression associated with diabetes in adults: evidence from longitudinal studies

Hasan, Syed Shahzad, Mamun, Abdulla A., Clavarino, Alexandra M., and Kairuz, Therese (2014) Incidence and risk of depression associated with diabetes in adults: evidence from longitudinal studies. Community Mental Health, 51 (2). pp. 204-210.

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Abstract

This meta-analysis examined depression as a consequence of diabetes by conducting a meta-analysis, using data from longitudinal studies. Databases were systematically searched for relevant studies. Incidence of depression is presented as cumulative incident proportion (CIP). Pooled effect sizes were calculated using randomeffects model. The data were reconstructed to compute relative risk (RR) and CIP. The 16 studies selected for review generated 16 datasets of which 11 studies reporting binary estimates (RR) and 5 studies reporting time-to-event estimates [hazard ratio (HR)]. Both RR and HR were significant at 1.27 (95 % CI 1.17–1.38) and 1.23 (95 % CI 1.08–1.40) for incident depression associated with diabetes mellitus. Our observations also revealed greater cumulative incidence of depression in diabetes than in non diabetes groups. Our study shows that diabetes is a significant risk factor for the onset of depression.

Item ID: 37744
Item Type: Article (Research - C1)
ISSN: 1573-2789
Keywords: depression, diabetes mellitus, longitudinal, meta-analysis
Date Deposited: 17 Mar 2015 03:55
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111503 Clinical Pharmacy and Pharmacy Practice @ 100%
SEO Codes: 92 HEALTH > 9202 Health and Support Services > 920205 Health Education and Promotion @ 100%
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