The double burden: a new-age pandemic meets an ancient infection

Bridson, Tahnee L., Govan, Brenda L., Norton, Robert E., Schofield, Louis, and Ketheesan, Natkunam (2014) The double burden: a new-age pandemic meets an ancient infection. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108 (11). pp. 676-678.

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Abstract

Tuberculosis is responsible for significant morbidity and mortality in the tropics. Active TB develops when host defences are impaired. Epidemiological evidence and studies addressing the double burden of communicable and non-communicable diseases demonstrate a clear association between diabetes and susceptibility to TB, treatment failure and complications. The immune mechanisms involved in host-pathogen interactions in co-morbid TB-diabetes are not well defined and require further investigation. This combined with the increase in diabetes predominately in low- and middle-income countries where TB is prevalent has major health implications.

Item ID: 37657
Item Type: Article (Commentary)
Keywords: diabetes, infectious diseases, tuberculosis, type 2 diabetes, susceptibility
ISSN: 1878-3503
Date Deposited: 04 Mar 2015 02:22
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110801 Medical Bacteriology @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110704 Cellular Immunology @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920104 Diabetes @ 50%
92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 50%
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