Abdominal aortic aneurysm calcification and thrombus volume are not associated with outcome following endovascular abdominal aortic aneurysm repair

Rai, Divyajeet, Wisniowski, Brendan, Bradshaw, Barbara, Velu, Ramesh, Tosenovsky, Patrik, Quigley, Francis, Walker, Philip J., and Golledge, Jonathan (2014) Abdominal aortic aneurysm calcification and thrombus volume are not associated with outcome following endovascular abdominal aortic aneurysm repair. European Radiology, 24 (8). pp. 1768-1776.

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Abstract

Objectives: Aortic calcification and thrombus have been postulated to worsen outcome following endovascular abdominal aortic aneurysm repair (EVAR). The purpose of this study was to assess the association of abdominal aortic aneurysm (AAA) calcification and thrombus volume with outcome following EVAR using a reproducible, quantifiable computed tomography (CT) assessment protocol.

Methods: Patients with elective EVAR performed between January 2002 and 2012 at the Townsville Hospital, Mater Private Hospital (Townsville) and Royal Brisbane and Women's Hospital (RBWH) were included if preoperative CTAs were available for analysis. AAA calcification and thrombus volume were measured using a semiautomated workstation protocol. Outcomes were assessed in terms of clinical failure, endoleak (type I, type II) and reintervention. Univariate and multivariate analyses were performed. Median follow-up was 1.7 years and the interquartile range 1.0-3.8 years.

Results: One hundred thirty-four patients undergoing elective EVAR were included in the study. Rates of primary clinical success and freedom from reintervention were 82.8 % and 88.9 % at the 24-month follow-up. AAA calcification and thrombus volume were not associated with clinical failure, type I endoleak, type II endoleak or reintervention.

Conclusions: AAA calcification and thrombus volume were not associated with poorer outcome after EVAR in this study.

Key Points:

The association of calcification and thrombus volumes with EVAR outcome is unclear

Quantifiable methods for assessing calcification and thrombus were not used previously

This study used reproducible methods for assessing AAA calcification and thrombus volumes.

Item ID: 36227
Item Type: Article (Research - C1)
ISSN: 1432-1084
Keywords: aortic aneurysm, abdominal (AAA), endoluminal repair, calcification, thrombus, tomography, X-Ray computed
Funders: Queensland Government, Townsville Hopsital, National Health and Medical Research Council
Date Deposited: 12 Nov 2014 12:42
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
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