Abdominal aortic calcification: clinical significance, mechanisms and therapies

Golledge, Jonathan (2014) Abdominal aortic calcification: clinical significance, mechanisms and therapies. Current Pharmaceutical Design, 20 (37). pp. 5834-5838.

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Abstract

Traditionally abdominal aortic calcification (AAC) has received less intensive study than coronary artery calcification. The widespread use of abdominal imaging has however encouraged recent investigation of this problem. Human association studies suggest that older age, chronic kidney disease and osteoporosis are the most important risk factors for AAC. AAC severity has been consistently associated with death and cardiovascular events and therefore there is growing interest in identifying potential therapies to limit AAC. At present there have only been a small number of well controlled trials designed to assess effective interventions for AAC. Further studies are expected over the coming years. Whether an intervention which effectively limits AAC will also reduce the incidence of cardiovascular events remains to be established.

Item ID: 36225
Item Type: Article (Research - C1)
ISSN: 1873-4286
Keywords: aorta, calcification, abdominal aortic calcification, cardiovascular events
Funders: Office of Health and Medical Research, Queensland Government, National Health and Medical Research Council (NHMRC), BUPA Health Foundation
Date Deposited: 12 Nov 2014 12:42
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
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