O'Neil, Adrienne, Taylor, Barr, Sanderson, Kristy, Cyril, Sheila, Chan, Bianca, Hawkes, Anna L., Hare, David L., Jelinek, Michael, Venugopal, Kamalesh, Atherton, John J., Amerena, John, Grigg, Leeanne, Walters, Darren L., and Oldenburg, Brian (2014) Efficacy and feasibility of a tele-health intervention for acute coronary syndrome patients with depression: results of the "MoodCare" randomized controlled trial. Annals of Behavioral Medicine, 48 (2). pp. 163-174.

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Abstract

Background: Depression is common after a cardiac event, yet there remain few approaches to management that are both effective and scalable.

Purpose: We aimed to evaluate the 6-month efficacy and feasibility of a tele-health program (MoodCare) that integrates depression management into a cardiovascular disease risk reduction program for acute coronary syndrome patients with low mood.

Methods: A two-arm, parallel, randomized design was used comprising 121 patients admitted to one of six hospitals for acute coronary syndrome.

Results: Significant treatment effects were observed for Patient Health Questionnaire 9 (PHQ9) depression (mean difference [change] = −1.8; p = 0.025; effect size: d = 0.36) for the overall sample, when compared with usual medical care. Results were more pronounced effects for those with a history of depression (mean difference [change] = −2.7; p = 0.043; effect size: d = 0.65).

Conclusions: MoodCare was effective for improving depression in acute coronary syndrome patients, producing effect sizes exceeding those of some face-to-face psychotherapeutic interventions and pharmacotherapy.

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