Murine cerebral malaria: the whole story

Hunt, Nicholas H., Grau, Georges E., Engwerda, Christian, Barnum, Scott R., van der Heyde, Henri, Hansen, Diana S., Schofield, Louis, and Golenser, Jacob (2010) Murine cerebral malaria: the whole story. Trends in Parasitology, 26 (6). pp. 272-274.

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[Extract] In the Opinion of White and colleagues [1], 'The value of the mouse model in identifying pathological processes or therapeutic interventions in human cerebral malaria is questionable.' Surprisingly, this conclusion was presented without discussion of any of the numerous similarities between the cerebral syndromes caused by Plasmodium falciparum in humans and the P. berghei ANKA strain in mice that have been described in several detailed reviews (for example, Refs 2 and 3).

Item ID: 35862
Item Type: Article (Commentary)
ISSN: 1471-5007
Date Deposited: 30 Oct 2014 06:09
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110799 Immunology not elsewhere classified @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970111 Expanding Knowledge in the Medical and Health Sciences @ 100%
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