γ-Glutamyltransferase, obesity, physical activity, and the metabolic syndrome in Indigenous Australian adults

Li, Ming, Campbell, Sandra, and McDermott, Robyn (2009) γ-Glutamyltransferase, obesity, physical activity, and the metabolic syndrome in Indigenous Australian adults. Obesity, 17 (4). pp. 809-813.

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View at Publisher Website: http://dx.doi.org/10.1038/oby.2008.617
 
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Abstract

The aim of this study is to examine the association between obesity, metabolic syndrome, physical activity, and elevated γ-glutamyltransferase (GGT) among Indigenous Australian adults who did not drink alcohol. A cross-sectional study of 791 Indigenous adults in rural North Queensland communities was conducted between 1999 and 2001. Measures included serum GGT, fasting glucose, cholesterol, and triglycerides; resting blood pressure, BMI, and waist circumference; and self-reported physical activity, alcohol intake, and tobacco smoking. Central obesity measured by waist circumference in this population was significantly associated with elevated GGT independently of lifestyle behaviors (Adjusted odds ratio (OR) = 2.7, 95% confidence interval (CI): 1.2–6.0). Metabolic syndrome (International Diabetes Federation definition) was also strongly associated with increased GGT (OR = 2.6, 95% CI: 1.5–4.6). Habitual physical activity may be slightly protective (OR = 0.9, 95% CI: 0.5–1.6) in this group, but this was not clearly demonstrated in this study. Prevention of type 2 diabetes and cardiovascular disease in this population should emphasize "waist loss" and metabolic health through dietary and other interventions.

Item ID: 35806
Item Type: Article (Research - C1)
ISSN: 1930-739X
Funders: National Health and Medical Research Council (NHMRC)
Projects and Grants: NHMRC grant number 279402
Date Deposited: 15 Oct 2014 16:48
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111701 Aboriginal and Torres Strait Islander Health @ 100%
SEO Codes: 92 HEALTH > 9203 Indigenous Health > 920301 Aboriginal and Torres Strait Islander Health - Determinants of Health @ 100%
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