Selenium, immune function and resistance to viral infections

Gill, Harsharn, and Walker, Glen (2008) Selenium, immune function and resistance to viral infections. Nutrition and Dietetics, 65 (Suppl 3). S41-S47.

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Abstract

Selenium (Se) is an essential micronutrient that, through its incorporation into selenoproteins, plays a pivotal role in maintaining optimal health. insufficient intake of Se enhances predisposition to diseases associated with oxidative stress to cells and tissues while supplementation above the recommended levels has been shown to confer health benefits such as enhanced immune competence and resistance to viral infections and in animal models and human studies. Recent studies have also shown that different sources of Se differ in their bioavailability and bioactivity and that Se-enriched milk may be a superior source of Se. In this paper, we briefly describe the nature of selenoproteins, sources of Se in diets and the known mechanisms by which Se/selenoproteins regulate redox balance, augment immune function and mediate resistance to viral infections.

Item ID: 35765
Item Type: Article (Research - C1)
ISSN: 1747-0080
Keywords: dairy, immune function, selenium, selenoprotein, viral infection
Funders: National Centre of Excellence in Functional Foods (Australia)
Date Deposited: 15 Oct 2014 16:46
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1111 Nutrition and Dietetics > 111199 Nutrition and Dietetics not elsewhere classified @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110799 Immunology not elsewhere classified @ 50%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920411 Nutrition @ 50%
92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920412 Preventive Medicine @ 50%
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