Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A., and Kairuz, Therese (2013) Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women. Diabetes & Metabolic Syndrome: clinical research & reviews, 7 (4). pp. 191-197.

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Aims: The aim of this study was to investigate the association between pregnancy complications, mental health-related problems, and type 2 diabetes mellitus (T2DM) in Malaysian women.

Materials and methods: A case–control study of women with T2DM (n = 160) matched by age range to controls without T2DM (n = 160). Data were collected in the Negeri Sembilan and PutraJaya regions in Malaysia, from two hospital outpatient clinics, PutraJaya Hospital and Tuanku Jaa'far Hospital Seremban, and one health clinic at Seremban. Validated, interviewer-administered questionnaires were used to obtain the data. The unadjusted and adjusted estimates were calculated using the Mantel–Haenszel method.

Results: Neither depression (RR 0.74, 95% CI: 0.39–1.41) nor anxiety (RR 1.00, 95% CI: 0.53–1.88) symptoms increased the risk of T2DM significantly. However, gestational diabetes (RR 1.35, 95% CI: 1.02–1.79), and ≥3 pregnancies (RR 1.39, 95% CI: 1.08–1.79) were significant risk factors for the development of T2DM. T2DM was not a significant risk factor for either depression (RR 1.26, 95% CI: 0.91–1.74) or anxiety symptoms (RR 1.13, 95% CI: 0.59–2.19).

Conclusion: In this study, T2DM is not a significant risk factor for depression and anxiety; similarly, neither are depression and anxiety significant risk factors for T2DM. Although prevalence of depression and anxiety is not alarming, the findings reported here should alert clinicians to screen and treat anxiety and depression in people with diabetes and also note the importance of monitoring women with complications in pregnancy for risk of later T2DM.

Item ID: 35001
Item Type: Article (Research - C1)
ISSN: 1871-4021
Keywords: type 2 diabetes mellitus, depression, anxiety, Malaysian, women
Date Deposited: 27 Aug 2014 03:35
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
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